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Effective weight loss with Rimonabant

Approximately 14% of the patients and rimonabant 20 mg / day summit put as a result of side effects, particularly depressed mood, although the overall rates of depression did not differ significantly compared with placebo. Place in therapy: The evidence supports the use of rimonabant 20 mg / day, along with dietary needs modification to reduce cardiovascular risk factors in patients with obesity and overweight, including those with diabetes. The medicine is contraindicated? Iceerd to patients and antidepressants. Long-term data on cardiovascular outcomes, morbidity and mortality are eagerly awaited. Key words: metabolic syndrome, obesity, rimonabant, diabetes type 2 Scope, aims and objectives The increasing global prevalence of obesity and overweight, and the related constellation of risk factors known as the metabolic syndrome (including dyslipidemia, insulin resistance, hypertension and vascular endothelial dysfunction ) are thought to underlie a growing epidemic of cardiovascular disease, diabetes and certain forms of cancer.

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This invariably increases the level for good HDL-cholesterol, lower triglycerides, and improves impaired levels of glucose and insulin. This reduces the risk of cardiovascular heart diseases and diabetes. Its developers Sanofi-Aventis claim that it is also found effective in assisting smokers to quit smoking. They are currently researching to determine the possible value of Rimonabant in smoking cessation therapy. It was actually found that smokers often experience extreme hunger pangs and it has been found that Endocannabinoid system plays a critical role in body's response to tobacco dependence. Hence they claim that by inhibiting the factors responsible for activating the Endocannabinoid system, one can not only shed off extra fats but also quit smoking.

Aug. 30, 2004 (Munich) -- An experimental diet drug continues to show promise in the battle against obesity, and may benefit those with multiple risk factors for health-related complications stemming from obesity. In the latest study of the drug rimonabant, overweight volunteers who took 20 milligrams of the drug daily for a year lost an average of 20 pounds and reduced their waist size by an average of over 3 inches. Rimonabant works by inhibiting the CB1 receptor, which works on a newly described network system called the endocannabinoid system (EC System). This system plays a critical role in the regulation of food intake and metabolism. This is the same drug that has shown promise as a smoking-cessation aid, helping smokers quit smoking, while losing rather than gaining weight.