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SAN DIEGO -- The investigational drug rimonabant produces highly significant cardiovascular and metabolic benefits in patients with type 2 diabetes, Andre Scheen, M. D., reported at the annual scientific sessions of the American Diabetes Association. Earlier this year, Sanofi-Aventis filed for U. S.and European licensure of the selective endo-cannabinoid type 1-receptor blocker, based on data from phase III trials involving more than 6,600 overweight and obese individuals in North America and Europe showing that the agent promotes sustained weight loss, improved cardiovascular risk profiles, and reversal of metabolic syndrome. Related Results Lancet, BMJ studies sound concern over anti-obesity drug rimonabantRimonabant improves cardiovascular risk profileRimonabant improves cardiovascular risk profileNew drug application for rimonabant pulledRimonabant enhanced weight loss success, improved lipids The latest of these trials, the Rimonabant in Obesity (RIO)-Diabetes study, suggests similar benefit among overweight and obese patients with type 2 diabetes."Patients with type 2 diabetes often have multiple cardiovascular risk factors.
