Welcome to: Rimonabant Information Source (rimonabant and 2007)

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4 lb (4. 7 kg). The percentage of patients achieving a clinically relevant (i.e., 10 percent or greater) weight loss was 25. 2 percent for patients receiving 20 mg rimonabant and 8. 5 percent for patients in the placebo group (number needed to treat for one year = 17); the difference between 5 mg rimonabant and placebo was not significant. Patients switching from the 20 mg rimonabant group to the placebo group during year 2 experienced weight gain, whereas those who continued to take 20 mg rimonabant did not. Bottom Line: Rimonabant is minimally effective in obese or overweight patients for achieving sustained weight loss. Less than one half of the patients initially enrolled in this study completed the protocol at one year.
