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But nearly three of four participants who got 20 mg doses of Acomplia lost at least 5% of their body weight -- and nearly half lost more than 10%. That's impressive weight loss for any clinical trial. But Despres says that people who took Acomplia lost the most dangerous pounds -- abdominal fat. Half of those who had metabolic syndrome no longer had the condition after treatment with the 20-milligram dose of Acomplia."I am very impressed in the increase in [good] HDL cholesterol generated by this one-year rimonabant therapy," Despres said."The 20-milligram dose was able to generate a 20% increase in HDL, accompanied by more than a 10% decrease in triglycerides [blood fats]. Those who completed the full study had even more spectacular results: a 25% increase in HDL.".
